I've got a tip for everyone with large collections of cards. Simply shuffle the lot together, and split them between however many players, and then play with huge decks! Then basically play the game like there was a crumbling sanctuary in play (take damage off the decks). Its good to use all those non-standard cards, and can really increase your strategic thinking.
Anyway, anyone played with unhinged cards? I think some of them are really good actually (and certainly funny). Just a tip, the best combo ever is a Wordmail with a, and i'll catch my breath before i say this... "Our Market Research Shows That Players Like Really Long Card Names So We Made This Card to Have the Absolute Longest Card Name Ever Elemental"...
And i'll leave you on a combo for you to think about. Your playing against a guy with a huge creature deck. Maybe they've got something like a denzian of the deep or something in play (i don't know, some huge card or other). A simple move is Ashnod's Transmogrant and Steal Artifact... always fun, i'm thinking.