Edexcel GCE Biology Unit 5 6BI05 June 2013

Reply 20

angelz.pari

heya evryone :smile:

can someone please help me identify the various themes used in this article

Reply 21

cupcake93

2

Hi everyone does anyone have the 'Possible Questions and Answers for the Scientific Article: June 2013 by Edexcel Biology Solutions Pack? If so could you please upload it onto this thread as I've heard that its useful Thankyou :smile:

Reply 22

himi-patel

....

(edited 11 years ago)

Reply 23

himi-patel

Original post by angelz.pari

heya evryone :smile:

can someone please help me identify the various themes used in this article

http://www.nature.com/scitable/topicpage/protein-misfolding-and-degenerative-diseases-14434929 check this link out you will understand paragraph 11 3rd to 5th line.....

Reply 24

jeya

can someone post practice questions.

Reply 25

jeya

Original post by Abod

I've read it. Before I start working on it, I will first read the previous ones and see what type of questions they ask.
No problem, donleone.

Came up with any questions

Reply 26

Harantony

10

My List of Topics, Questions and Parts of the Specification

How Science Works:

Validity, reliability, peer review and how findings are presented to the scientific community

7 How Science Works, Point

11 How Science Works, Point

Example

1.

Paragraph 7: "In general, lifespan tends to correlate with body size".
Another study concluded that a larger body size caused a longer lifespan. Explain why this may not be a valid conclusion.

2.

Correlation does not necessarily mean causation.

3.

In general - if size caused the lifespan to change, then the statement would always be true.

4.

Not enough data may have been collected to prove that the correlation is a causation.

5.

Suggest how the conclusions of the investigations conducted could be accepted by the scientific community.

6.

Publish results in scientific journals

7.

Present results at conferences

8.

Peer review

9.

Any explanation for peer review (e.g. scientists in the same field conduct the experiment to check its validity whether the results are similar).

Testing on animals - risks and benefits

9 How Science Works, Point

Example

1.

Paragraph 53: "With naked mole-rats, we have to start from scratch with many things".
What are the advantages and disadvantages of using mole-rats (use your own knowledge, the article and the sentence above)?

2.

It can impact the development of new treatments, theories etc. and therefore impact the rate of helping other humans.

3.

It is expensive and time-consuming to sequence the genome of the mole-rat.

4.

The mole-rats may be more useful in terms of physiology and behaviour than mice.

5.

Mole-rats are animals with a nervous system, so may be more unethical to test with (as with mice).

6.

Mole-rats live for a relatively long time, so can be studied in the long-term too.

7.

The behaviour of mole-rats may differ ex-situ (e.g. the Queen not being present can change behaviour); the living conditions cannot be recreated.

Unit 1:

Paragraph 2 - The mole rats can help tackle strokes
Paragraph 7 - They don't show signs of heart disease
Paragraph 36 - Findings can give treatment for heart attacks and strokes

Topic 1, Points 10-15

Example

1.

Using a named factor that can cause cardiovascular disease, explain how a stroke can arise.

2.

Name and explain two current treatments for cardiovascular disease.

3.

Describe two ways in which coronary heart disease can be prevented.

Paragraph 38 - Hypoxia adaptations in the lungs (gas exchange surface)
Paragraph 9 - DNA and proteins - attachment of other molecules
Paragraph 11 - 3D shape of proteins and importance (misfolding proteins can relate to CF [CFTR protein] too)
Paragraph 15 - DNA replication (cancer mentioned throughout [e.g. paragraph 20] - a mutation can cause cancer; how does this arise?)

Topic 2, Points 6-15 (Excluding some)

Example

1.

Why is the 3D structure of proteins critical to functioning?

I've stopped here, but have posted it as some starting help. I can't guarantee that I can get any more done myself, so if you have any that you can think of (across all units and topic of the A Level), then quote me and I'll add it.

Terms to Research:

•

Eusocial Society

•

Poikilothermic

•

Homeotherm

•

Oxidative Stress

•

Contact Inhibition

•

Monomorphic

•

Leuteinizing Hormone

•

Systemic Hypoxia

If you feel like any answers should be added to (or you think of any other questions, specification points or anything else that should be added/changed), quote me the problem and I'll change it. :smile:

(edited 11 years ago)

Reply 27

thegreenchildren

9

Hey I am also doing this exam. So have people finished their A2 coursework now?

Reply 28

Hdizzle

9

Original post by thegreenchildren

Hey I am also doing this exam. So have people finished their A2 coursework now?

We did our A2 coursework last summer after the exams
One thing less to stress about

Reply 29

thegreenchildren

9

Original post by Hdizzle

We did our A2 coursework last summer after the exams
One thing less to stress about

Wow that's an awesome idea. I think my teacher wanted us to do it now because we could use A2 knowledge in it as that's important apparently. Did you use A2 knowledge as well?

Reply 30

Hdizzle

9

Original post by Harantony

My List of Topics, Questions and Parts of the Specification

How Science Works:

Validity, reliability, peer review and how findings are presented to the scientific community

11 How Science Works, Point

Example

1.

Paragraph 7: "In general, lifespan tends to correlate with body size".
Another study concluded that a larger body size caused a longer lifespan. Explain why this may not be a valid conclusion.

2.

Correlation does not necessarily mean causation.

3.

In general - if size caused the lifespan to change, then the statement would always be true.

4.

Not enough data may have been collected to prove that the correlation is a causation.

5.

Suggest how the conclusions of the investigations conducted could be accepted by the scientific community.

6.

Publish results in scientific journals

7.

Present results at conferences

8.

Peer review

9.

Any explanation for peer review (e.g. scientists in the same field conduct the experiment to check its validity whether the results are similar).

Testing on animals - risks and benefits

Example

1.

Paragraph 53: "With naked mole-rats, we have to start from scratch with many things".
What are the advantages and disadvantages of using mole-rats (use your own knowledge, the article and the sentence above)?

2.

It can impact the development of new treatments, theories etc. and therefore impact the rate of helping other humans.

3.

It is expensive and time-consuming to sequence the genome of the mole-rat.

4.

The mole-rats may be more useful in terms of physiology and behaviour than mice.

5.

Mole-rats are animals with a nervous system, so may be more unethical to test with (as with mice).

6.

Mole-rats live for a relatively long time, so can be studied in the long-term too.

7.

The behaviour of mole-rats may differ ex-situ (e.g. the Queen not being present can change behaviour); the living conditions cannot be recreated.

Unit 1:

Paragraph 2 - The mole rats can help tackle strokes
Paragraph 7 - They don't show signs of heart disease
Paragraph 36 - Findings can give treatment for heart attacks and strokes

Topic 1, Points 10-15

Example

1.

Using a named factor that can cause cardiovascular disease, explain how a stroke can arise.

2.

Name and explain two current treatments for cardiovascular disease.

3.

Describe two ways in which coronary heart disease can be prevented.

Paragraph 38 - Hypoxia adaptations in the lungs (gas exchange surface)
Paragraph 9 - DNA and proteins - attachment of other molecules
Paragraph 11 - 3D shape of proteins and importance (misfolding proteins can relate to CF [CFTR protein] too)
Paragraph 15 - DNA replication (cancer mentioned throughout [e.g. paragraph 20] - a mutation can cause cancer; how does this arise?)

Topic 2, Points 6-15 (Excluding some)

Example

1.

Why is the 3D structure of proteins critical to functioning?

I've stopped here, but have posted it as some starting help. I can't guarantee that I can get any more done myself, so if you have any that you can think of (across all units and topic of the A Level), then quote me and I'll add it.

Terms to Research:

•

Eusocial Society

•

Poikilothermic

•

Homeotherm

•

Oxidative Stress

•

Contact Inhibition

•

Monomorphic

•

Leuteinizing Hormone

•

Systemic Hypoxia

If you feel like any answers should be added to (or you think of any other questions, specification points or anything else that should be added/changed), quote me the problem and I'll change it. :smile:

Paragraph 1
Ethics of animal testing: utilitarian approach to animal testing- working for greater good.

Paragraph 3
Adaptations of nekked mole rat to environment:
Large teeth to burrow with underground
No fur as they live in hot conditions therefore not required
Due to dark underground conditions they are dependent on their heightened sense of smell, whiskers used as pressure points

Paragraph 4
Part of eusocial society where queen bee is only actively reproducing female and only a hand full of actively reproducing males. Everyone else is infertile. This constant in breeding results in reduction of genetic variation (which reduces chances of speciation)

Possible question may be 'how is genetic variation obtained?'
-independent assortment
-crossing over
-random fertilisation

What are disadvantages of having no genetic variation?

Paragraph 5
Comparing homeotherms (like humans-we regulate our body temperature) to poikilotherms-those whose body temperature is dependent on environmental temperature.

There may be a question with regards to homeostasis in humans and regulating body temp?

Paragraph 6
...notice how they constantly put name of specialist, area they specialise in and the institution they work at-highlights credibility of sources

So question may be on how scientists ensure results produced etc are ensured to be reliable and valid
--

That's all so far

Hope may be of some help

Paragraph 13- remember that stuff on the tumour suppressor protein..? Might be relevant
Its from unit 2

(edited 11 years ago)

Reply 31

Hdizzle

9

Original post by thegreenchildren

Wow that's an awesome idea. I think my teacher wanted us to do it now because we could use A2 knowledge in it as that's important apparently. Did you use A2 knowledge as well?

Well everyone came out with really high marks (A*'s-B's) so I guess we did write to A2 standard in our chosen topic area

I did mine on the eye

Lots of people did photosynthesis, enzymes, ecological study, memory and the eye

Reply 32

jeya

Original post by Harantony

My List of Topics, Questions and Parts of the Specification

How Science Works:

Validity, reliability, peer review and how findings are presented to the scientific community

11 How Science Works, Point

Example

1.

Paragraph 7: "In general, lifespan tends to correlate with body size".
Another study concluded that a larger body size caused a longer lifespan. Explain why this may not be a valid conclusion.

2.

Correlation does not necessarily mean causation.

3.

In general - if size caused the lifespan to change, then the statement would always be true.

4.

Not enough data may have been collected to prove that the correlation is a causation.

5.

Suggest how the conclusions of the investigations conducted could be accepted by the scientific community.

6.

Publish results in scientific journals

7.

Present results at conferences

8.

Peer review

9.

Any explanation for peer review (e.g. scientists in the same field conduct the experiment to check its validity whether the results are similar).

Testing on animals - risks and benefits

Example

1.

Paragraph 53: "With naked mole-rats, we have to start from scratch with many things".
What are the advantages and disadvantages of using mole-rats (use your own knowledge, the article and the sentence above)?

2.

It can impact the development of new treatments, theories etc. and therefore impact the rate of helping other humans.

3.

It is expensive and time-consuming to sequence the genome of the mole-rat.

4.

The mole-rats may be more useful in terms of physiology and behaviour than mice.

5.

Mole-rats are animals with a nervous system, so may be more unethical to test with (as with mice).

6.

Mole-rats live for a relatively long time, so can be studied in the long-term too.

7.

The behaviour of mole-rats may differ ex-situ (e.g. the Queen not being present can change behaviour); the living conditions cannot be recreated.

Unit 1:

Paragraph 2 - The mole rats can help tackle strokes
Paragraph 7 - They don't show signs of heart disease
Paragraph 36 - Findings can give treatment for heart attacks and strokes

Topic 1, Points 10-15

Example

1.

Using a named factor that can cause cardiovascular disease, explain how a stroke can arise.

2.

Name and explain two current treatments for cardiovascular disease.

3.

Describe two ways in which coronary heart disease can be prevented.

Paragraph 38 - Hypoxia adaptations in the lungs (gas exchange surface)
Paragraph 9 - DNA and proteins - attachment of other molecules
Paragraph 11 - 3D shape of proteins and importance (misfolding proteins can relate to CF [CFTR protein] too)
Paragraph 15 - DNA replication (cancer mentioned throughout [e.g. paragraph 20] - a mutation can cause cancer; how does this arise?)

Topic 2, Points 6-15 (Excluding some)

Example

1.

Why is the 3D structure of proteins critical to functioning?

I've stopped here, but have posted it as some starting help. I can't guarantee that I can get any more done myself, so if you have any that you can think of (across all units and topic of the A Level), then quote me and I'll add it.

Terms to Research:

•

Eusocial Society

•

Poikilothermic

•

Homeotherm

•

Oxidative Stress

•

Contact Inhibition

•

Monomorphic

•

Leuteinizing Hormone

•

Systemic Hypoxia

If you feel like any answers should be added to (or you think of any other questions, specification points or anything else that should be added/changed), quote me the problem and I'll change it. :smile:

thanx for da Q

Reply 33

viper10

Original post by angelz.pari

heya evryone :smile:

can someone please help me identify the various themes used in this article

hi, i'm also sitting for this exam. could you also help me with this information on the themes in the article

Reply 34

Abod

3

download

I've been negged for the broken link -.-
Fixed it.

(edited 10 years ago)

Reply 35

TheNoobyPotato

Maybe all the pre release information and questions everyone is coming up with should be collected or linked in the first post?

Posted from TSR Mobile

Reply 36

Abod

3

Good idea but too much effort for OP. + Last Activity 1 Week Ago

Reply 37

Abod

3

42. “We believe that the extreme resistance to oxygen deprivation is a result of evolutionary adaptations
for surviving in a chronically low-oxygen environment,” said Park.

This is an example of Behavioural Adaptation, right?