Well I've lived all my life (apart from 3 years away for Uni) in High Wycombe or just outside it.
Sorry to disappoint but from a clubbing point of view wycombe isn't the place to be. If you're going clubbing from Wycombe then London is the best option. High Wycombe offers Pure or Yates as far as "clubs" go. Average at best.
There are a range of pubs though, I personally go to the Antelope as my mates do, although the god awful toilets and overall setup aren't great. There are lots of pubs dotted around though. There is Butlers, Falcon, William Loosely which are popular at the weekends.
There is the student union for you guys though, which I managed to get into once, wasn't bad, live music etc.
I hope I've sufficiently lowered your expectations of clubs, but not disappointed too much about pubs?
Have a good time.
P.S. A pint in return would be nice, remember, The Antelope