It says on Wikipedia that you can get liquid forms of it for people who can't swallow tablets, so it could be that it will affect it if you crush it up.
I would have thought (PLEASE don't take my advice though!) that if the tablet is coated, or if it's a capsule, that you can't crush it and dissolve the powder, because the coating is there to delay its absorption. But if it's just a compressed powder tablet, you might be alright...PLEASE don't go by my meandering thoughts though! Maybe go back to the pharmacist or doctors and ask if it's ok to take as a powder, or get the liquid prescribed...