EDEXCEL Biology JUNE 2012 Pre-release article

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Reply 180

This Honest

Guys,

How would you outline the stages of gene expression

Reply 181

iesians

ok im doomed, I CANNOT UNDERSTAND A SINGLE WORD FROM THE ARTICLE !!

Reply 182

hello123450

Original post by CDM92

hello

in paragraph 22, page 4 of the scientific article, what is meant by 'withdrawal-like state seen in drug dependence'? really dont understand in the context of the article. thanks! :smile:

there is a file with annotations along the side of the article (someone posted the download link above :smile:

)
but anyways, on that file the annotations highlight those words:

withdrawal-like state: Those side effects experienced by a person who has become physically dependent on a substance, upon decreasing the substance's dosage or discontinuing its use.

drug dependence: a physical or psychologic state in which a person displays withdrawal symptoms if drug use is halted suddenly; can lead to addiction.

Hope this helps you! =]

Reply 183

Sheo

Original post by This Honest

Guys,

How would you outline the stages of gene expression

Hmm from what I remember from Unit 2 Markschemes it's normally

-Some genes are switched on/switched off
-Active genes(switched on genes) are transcribed to form mRNA
- mRNA translated at the ribosome to form protein
- Protein produced permanently modifies cell/ causing it to become specialised for one particular function

.. I'm not sure if this is exactly what you are looking for but it's what I learnt :smile:

Reply 184

This Honest

Original post by Sheo

Ahhhhh yhhh flip sake, i didn't see 'differential' so I was stuck lol cheers :smile:

Reply 185

Bright

I am so behind with unit 5 biology :frown:

...

Reply 186

d_94

Original post by Bright

I am so behind with unit 5 biology :frown:

...

Youre not alone. Me too :'( God its soo hard :/

Reply 187

Bright

Original post by d_94

Youre not alone. Me too :'( God its soo hard :/

I know! It's not that I need to revise.. I haven't even learned the stuff yet! :/

Reply 188

-James-

Original post by hello123450

there is a file with annotations along the side of the article (someone posted the download link above :smile:

please would you be able to provide a link or attachment for this annotated article ?

Reply 189

SLlewellyn

Just wondered how other people would answer the question "Outline a mechanism by which a drug could stimulate the sympathetic nervous system" (2 marks). - I went along the line of drug acting/mimicking a neurotransmitter and relaying action potentials/stimulating action potentials via the synapses.

Also, "Describe the steps by which mice could be engineered to produce high levels of PRDM16 proten" (5 marks). Cheers.

Reply 190

hello123450

Original post by -James-

please would you be able to provide a link or attachment for this annotated article ?

https://rapidshare.com/#!download|830p6|863680783|88808663-Scientific-Article-for-Use-With-Question-7-WITH-COMMENTS-by-STAFFORD.pdf|509|R~D30A96D1B5277CADB1EB25DF2F4A6C69|0|0

when you open it, just click download :smile:

Reply 191

k121op

become a member of this group-
https://www.facebook.com/groups/391604670885735/

Reply 192

-James-

Original post by hello123450

Thank youuu :biggrin:

Reply 193

d_94

Original post by hello123450

Woww. Thanks soo muchh !(:

Reply 194

hello123450

Original post by d_94

Woww. Thanks soo muchh !(:

its fineee (: i found the link on this thread anyways haha..
but yeahh, its SO helpful!! good luck. =]

Reply 195

d_94

Original post by hello123450

its fineee (: i found the link on this thread anyways haha..
but yeahh, its SO helpful!! good luck. =]

Thankss. U too.
Got any predictions on what might come up?

Reply 196

cisne

hei...i was wondering.....can we all discuss the questions we got from our teachers??? It'll be really helpful....

Reply 197

avataraang

Original post by SLlewellyn

Ok let me give this is a shot. (It may be wrong!)

A drug could stimulate the sympathetic nervous system by mimicing the neurotransmitter by having a similar molecular shape, causing the drug to bind to its complimentary receptor and stimulate action potentials by making the postsynaptic neurone more permeable to Na+ ions, causing depolarisation.

A GMO is created by the following procedure:
* A vector such as a virus is used and is genetically modified to insert the PRDM16 protein.
* This is inserted into the mice by an injection and binds to complementary receptors on the cells, releasing the GM DNA into the cell.
* New DNA then enters the nucleus and is integrated into the host cell genome.
* Transcription, translation etc then occurs, producing high levels of PRDM16.

Hope that is enough (or even right) for 5 marks

Reply 198

Kate Beckett

Can somebody please give me the link for jan 2012 unit 4 and 5 mark schemes and question paper, in the edexcel website u need a password and username and i dont hav one..

Reply 199

d_94

Original post by Kate Beckett

Can somebody please give me the link for jan 2012 unit 4 and 5 mark schemes and question paper, in the edexcel website u need a password and username and i dont hav one..