I've only done weed. and it was fine everytime.
But then one day I smoked what they call a virgin joint. basically strong weed without tobacco and that ****ed me up that night and I went seriously paranoid, but I'm sure there was something else in the weed because the reaction was extremely strong and lasted for a long time, feelings of past/future etc and it took me a while to feel normal again and resume a normal state of thinking to be honest, so I'm not sure what was in that joint, but it was smething prety strong, I went roaming around the city on my own like 100mph and paranoid as hell.
Since that day, never again.
Alcohol always makes me happy and have a good night, no matter how much I drink, so I'll just stick to that. Although I have nothing agaisnt my mates if they want to take psychedelic drugs, I would too, but it's just that night scared me away from drugs, I think my mind is too introverted/sensitive to be doing drugs. Haha.