The Student Room Group

Genetics Pedigree Q

okdowiqfjnie.jpg
(d) Are any recombinant progeny produced? If so, can you estimate
an approximate recombination frequency between the two loci?

(e) In another pedigree, Alice has two brothers and an uncle on her
mother's side who all suffer from haemophilia A. Alice's father is
colour blind but she and her brothers have normal colour vision.
Alice marries a colour blind man. Their first child is a haemophiliac
boy with normal colour vision. They produce two daughters, one
normal and one colour blind. Using the recombination frequency
deduced in part (d), what probabilities would you give these two girls
that they are carriers of haemophilia A? Show the probable genotypes
of all individuals on a pedigree.

part(d), Recombination frequency = 1/10
and part(e) I drew the pedigree, but I do not understand how to get the probabilities for the carriers of haemophilia, (answer is 10% and 90% for colour blind girl and normal respectively)
Help is appreciated.

Quick Reply

Latest