difference between adrenaline & noradrenaline

Biology discussion, revision, exam and homework help.

Announcements Posted on
Ask me ANYTHING - Andrew O'Neill - Buzzcocks comedian, amateur occultist, vegan... 22-05-2013
IMPORTANT: You must wait until midnight (morning exams)/4.30AM (afternoon exams) to discuss Edexcel exams and until 1pm/6pm the following day for STEP and IB exams. Please read before posting, including for rules for practical and oral exams. 28-04-2013
Sign in to Reply
  1. shimmerinapple's Avatar
    • Exalted Member
    difference between adrenaline & noradrenaline
    Is it that adrenaline is secreted by endocrine gland and noradrenaline is secreted by the sympathethic system? Or are they the same thing.
  2. aSian_cUtY's Avatar
    • Exalted and Worshipped Member
    Re: difference between adrenaline & noradrenaline
    Noradrenaline is secreted by the sympathetic division to speed up heart rate, breathing etc. Just remember S.I.N....Sympathetic is Noradrenaline :P

    Parasympathetic is aceytlcholine...slows down heart rate, breathing!!
  3. Dimez's Avatar
    • Vengeful, Imperial Overlord of The Student Room
    • Location: Compton
    Re: difference between adrenaline & noradrenaline
    ^^ You haven't answered the question.

    Not much of a difference TBH (apart from the prefix), they both have the same functions.

    I doubt any exam board would ask you to differentiate between the two anyhow.
  4. shimmerinapple's Avatar
    • Exalted Member
    Re: difference between adrenaline & noradrenaline
    I know they probably wont' ask something like that but I was curious.
  5. j00ni's Avatar
    • Peer Of The TSR Realm
    • Location: Preston
    • Posts: 1,474
    Re: difference between adrenaline & noradrenaline
    Adrenaline is a breakdown product of Noradrenaline. Both are produced within chromaffin cells of the adrenal medulla.

    Tyrosine is the starter molecule for both. It is broken down in the cytoplasm to form DOPA, which in turn is broken down into dopamine. Dopamine is then taken up into the granules where it is broken down into noradrenaline (in the presence of the enzyme catalyst Dopamine-B-hydroxylase).

    15% of the noradrenaline produced is stored for release. The rest re-enters the cytoplasm where it is further broken down into adrenaline in the presence of PEA-N-methyltransferase. It is then taken back up for storage in the granules, ready for release.

    The release of both is stimulated by the sympathetic nervous system (NA released directly from sympathetic ganglia, adrenaline being released from the adrenal glands under stimulation from the sympathetic nervous system).

    Adrenaline tends to act more strongly on beta receptors (e.g. lipolysis, incr. insulin secretion, incr. heart rate, incr. arteriolar dilation - therefore decr. BP)

    NA tends to act more strongly at alpha receptors (e.g. decr. insulin secretion, arteriolar constriction - therefore incr. BP, sphincter contraction, sweating, pupil dilation)

    Both act to increase glycogenolysis, gluconeogenesis and cardia contraction (as these are stimulated by both alpha and beta receptors)


    Well you did ask :p:
    Last edited by j00ni; 14-06-2006 at 08:43.
  6. Miss Amy's Avatar
    • Full Member
    • Location: Cardiff
    • Posts: 78
    Re: difference between adrenaline & noradrenaline
    (Original post by aSian_cUtY)
    Noradrenaline is secreted by the sympathetic division to speed up heart rate, breathing etc. Just remember S.I.N....Sympathetic is Noradrenaline :P
    S.I.N .....thats quite helpful
  7. Sophie01's Avatar
    • Banned
    • Location: Manchester
    • Posts: 288
    Re: difference between adrenaline & noradrenaline
    (Original post by Miss Amy)
    S.I.N .....thats quite helpful
    We remember it by SNAP( or PANS), whichever's easier.

    Sympathetic= Noradrenaline, Acetylcholine= Parasympathetic

  8. Comp_Genius's Avatar
    • TSR Demigod
    • Location: Earth
    • Posts: 5,464
    Re: difference between adrenaline & noradrenaline
    they are both transmitters of the sympathetic nervous system - the only difference is that adrenaline is from the methylation of noradrenaline. They both act on the same receptors although with different affinities
  9. Comp_Genius's Avatar
    • TSR Demigod
    • Location: Earth
    • Posts: 5,464
    Re: difference between adrenaline & noradrenaline
    (Original post by Sophie01)
    We remember it by SNAP( or PANS), whichever's easier.

    Sympathetic= Noradrenaline, Acetylcholine= Parasympathetic

    this is true only for postganglionic fibres - transmission from pre-ganglionic to post-ganglionic, sympathetic or parasympathetic - involves acetylcholine
  10. Saffie's Avatar
    • TSR Legend
    • Location: everywhere
    • Posts: 11,209
    Re: difference between adrenaline & noradrenaline
    in psychology AS I was taught that adrenaline was used in the sympathetic response and noradrenaline in the parasympathetic response. Quite strange...
  11. asianangel86's Avatar
    • Benevolent Member
    • Location: Sesame Street
    Re: difference between adrenaline & noradrenaline
    (Original post by aSian_cUtY)
    Parasympathetic is aceytlcholine...slows down heart rate, breathing!!
    S.I.N, i.e. stupid indian ninja.
    P.I.A, i.e. pakistani international airlines. thanks! i shall semember that!
  12. aSian_cUtY's Avatar
    • Exalted and Worshipped Member
    Re: difference between adrenaline & noradrenaline
    (Original post by asianangel86)
    S.I.N, i.e. stupid indian ninja.
    P.I.A, i.e. pakistani international airlines. thanks! i shall semember that!
    HAHAHA funnily enough i had P.I.A as my second one but i didnt think people would know what i was on about!
  13. Revenged's Avatar
    • Vengeful, Imperial Overlord of The Student Room
    • Location: .
    • Posts: 4,573
    Re: difference between adrenaline & noradrenaline
    (Original post by Saffie)
    in psychology AS I was taught that adrenaline was used in the sympathetic response and noradrenaline in the parasympathetic response. Quite strange...
    Noradrenaline and adrenaline are both produced in the sympathetic responce...

    It is acetylcholine that is produced in the parasympathetic responce...
  14. Saffie's Avatar
    • TSR Legend
    • Location: everywhere
    • Posts: 11,209
    Re: difference between adrenaline & noradrenaline
    (Original post by Revenged)
    Noradrenaline and adrenaline are both produced in the sympathetic responce...

    It is acetylcholine that is produced in the parasympathetic responce...
    i didn't say that they weren't :p:

    (just saying that psych AS is wrong (or bio A2 is, but I won't take the risk!))
    Last edited by Saffie; 17-06-2006 at 23:07.
  15. CharleeB's Avatar
    • Overlord in Training
    • Location: London
    • Posts: 2,007
    Re: difference between adrenaline & noradrenaline
    wow you guys know so much biology :| noones taught me any of this *decides shes going to fail*
  16. j00ni's Avatar
    • Peer Of The TSR Realm
    • Location: Preston
    • Posts: 1,474
    Re: difference between adrenaline & noradrenaline
    (Original post by CharleeB)
    wow you guys know so much biology :| noones taught me any of this *decides shes going to fail*
    Don't be disheartened, my, darkenergy and parts of other's posts is degree/post-A2 level requirements of knowledge - personally, I tend to go for overkill in replies, because too much information won't make someone fail - and if what I post isn't understood, or needs clarifying I would rather do it that way than have to keep adding to it. For A level I wouldn't have thought you need to know more than that the sympathetic nervous system uses NA (and adrenaline), and the parasympathetic uses ACh.

    Having said that when I did A2 AQA biology we only needed to know about ACh - it could have changed in the 4 years since i did it though

    /edit: god is it really 4 years, seems like yesterday
    Last edited by j00ni; 18-06-2006 at 15:04.
  17. Comp_Genius's Avatar
    • TSR Demigod
    • Location: Earth
    • Posts: 5,464
    Re: difference between adrenaline & noradrenaline
    (Original post by j00ni)
    Don't be disheartened, my, darkenergy and parts of other's posts is degree/post-A2 level requirements of knowledge - personally, I tend to go for overkill in replies, because too much information won't make someone fail - and if what I post isn't understood, or needs clarifying I would rather do it that way than have to keep adding to it. For A level I wouldn't have thought you need to know more than that the sympathetic nervous system uses NA (and adrenaline), and the parasympathetic uses ACh.

    Having said that when I did A2 AQA biology we only needed to know about ACh - it could have changed in the 4 years since i did it though

    /edit: god is it really 4 years, seems like yesterday
    I never knew that for A-level Biology... I did Edexcel which explains it. (it stands for something and excellence I believe. )
  18. danielf90's Avatar
    • Overlord in Training
    • Location: London
    • Posts: 2,041
    Re: difference between adrenaline & noradrenaline
    (Original post by shimmerinapple)
    Is it that adrenaline is secreted by endocrine gland and noradrenaline is secreted by the sympathethic system? Or are they the same thing.
    noradrenaline is called so because it does not have the R group that adrenaline does...it should read no-R-adrenaline...basically theres a CH3 group missing from the end of it.....

    [EDIT:] interesting or what?!
    Last edited by danielf90; 19-06-2006 at 16:54.
  19. so_this_is_sam's Avatar
    • Peer Of The TSR Realm
    • Location: England
    • Posts: 2,001
    Re: difference between adrenaline & noradrenaline
    i think the synoptic actually did ask something on noradrenaline because i remember lookin at the past paper and thinking...i have never even learnt any of this....
  20. iceman_jondoe's Avatar
    • TSR Demigod
    • Location: London/Exeter/Leeds
    • Posts: 5,343
    Re: difference between adrenaline & noradrenaline
    (Original post by aSian_cUtY)
    HAHAHA funnily enough i had P.I.A as my second one but i didnt think people would know what i was on about!
    i realise this is a year or two late but thats incredibly helpful!
Sign in to Reply
Share this discussion:  
Article updates
Moderators

We have a brilliant team of more than 60 volunteers looking after discussions on The Student Room, helping to make it a fun, safe and useful place to hang out.

Reputation gems:
The Reputation gems seen here indicate how well reputed the user is, red gem indicate negative reputation and green indicates a good rep.
Post rating score:
These scores show if a post has been positively or negatively rated by our members.