difference between adrenaline & noradrenaline
Biology discussion, revision, exam and homework help.
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Re: difference between adrenaline & noradrenaline
Adrenaline is a breakdown product of Noradrenaline. Both are produced within chromaffin cells of the adrenal medulla.
Tyrosine is the starter molecule for both. It is broken down in the cytoplasm to form DOPA, which in turn is broken down into dopamine. Dopamine is then taken up into the granules where it is broken down into noradrenaline (in the presence of the enzyme catalyst Dopamine-B-hydroxylase).
15% of the noradrenaline produced is stored for release. The rest re-enters the cytoplasm where it is further broken down into adrenaline in the presence of PEA-N-methyltransferase. It is then taken back up for storage in the granules, ready for release.
The release of both is stimulated by the sympathetic nervous system (NA released directly from sympathetic ganglia, adrenaline being released from the adrenal glands under stimulation from the sympathetic nervous system).
Adrenaline tends to act more strongly on beta receptors (e.g. lipolysis, incr. insulin secretion, incr. heart rate, incr. arteriolar dilation - therefore decr. BP)
NA tends to act more strongly at alpha receptors (e.g. decr. insulin secretion, arteriolar constriction - therefore incr. BP, sphincter contraction, sweating, pupil dilation)
Both act to increase glycogenolysis, gluconeogenesis and cardia contraction (as these are stimulated by both alpha and beta receptors)
Well you did ask
Last edited by j00ni; 14-06-2006 at 08:43. -
Re: difference between adrenaline & noradrenalinethis is true only for postganglionic fibres - transmission from pre-ganglionic to post-ganglionic, sympathetic or parasympathetic - involves acetylcholine(Original post by Sophie01)
We remember it by SNAP( or PANS), whichever's easier.
Sympathetic= Noradrenaline, Acetylcholine= Parasympathetic
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Re: difference between adrenaline & noradrenalineNoradrenaline and adrenaline are both produced in the sympathetic responce...(Original post by Saffie)
in psychology AS I was taught that adrenaline was used in the sympathetic response and noradrenaline in the parasympathetic response. Quite strange...
It is acetylcholine that is produced in the parasympathetic responce... -
Re: difference between adrenaline & noradrenalinei didn't say that they weren't(Original post by Revenged)
Noradrenaline and adrenaline are both produced in the sympathetic responce...
It is acetylcholine that is produced in the parasympathetic responce...
(just saying that psych AS is wrong (or bio A2 is, but I won't take the risk!))Last edited by Saffie; 17-06-2006 at 23:07. -
Re: difference between adrenaline & noradrenalineDon't be disheartened, my, darkenergy and parts of other's posts is degree/post-A2 level requirements of knowledge - personally, I tend to go for overkill in replies, because too much information won't make someone fail - and if what I post isn't understood, or needs clarifying I would rather do it that way than have to keep adding to it. For A level I wouldn't have thought you need to know more than that the sympathetic nervous system uses NA (and adrenaline), and the parasympathetic uses ACh.(Original post by CharleeB)
wow you guys know so much biology :| noones taught me any of this *decides shes going to fail*
Having said that when I did A2 AQA biology we only needed to know about ACh - it could have changed in the 4 years since i did it though
/edit: god is it really 4 years, seems like yesterdayLast edited by j00ni; 18-06-2006 at 15:04. -
Re: difference between adrenaline & noradrenalineI never knew that for A-level Biology... I did Edexcel which explains it. (it stands for something and excellence I believe.(Original post by j00ni)
Don't be disheartened, my, darkenergy and parts of other's posts is degree/post-A2 level requirements of knowledge - personally, I tend to go for overkill in replies, because too much information won't make someone fail - and if what I post isn't understood, or needs clarifying I would rather do it that way than have to keep adding to it. For A level I wouldn't have thought you need to know more than that the sympathetic nervous system uses NA (and adrenaline), and the parasympathetic uses ACh.
Having said that when I did A2 AQA biology we only needed to know about ACh - it could have changed in the 4 years since i did it though
/edit: god is it really 4 years, seems like yesterday
)
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Re: difference between adrenaline & noradrenalinenoradrenaline is called so because it does not have the R group that adrenaline does...it should read no-R-adrenaline...basically theres a CH3 group missing from the end of it.....(Original post by shimmerinapple)
Is it that adrenaline is secreted by endocrine gland and noradrenaline is secreted by the sympathethic system? Or are they the same thing.
[EDIT:] interesting or what?!Last edited by danielf90; 19-06-2006 at 16:54.