Well anti-quarks will have a quark number of -1 and quarks a quark number of +1. So the LHS has +4 and so does the RHS. So quarks have to be conserved just like leptons are.
Strangeness is a component of strange quarks. It's not about whether there is a strong interaction or not. All strange quarks have a strangeness of -1 and all anti-strange quarks have a strangeness of +1. The interaction will always involve the strong nuclear force when quarks are involved, if that's what you meant by strong interaction.
There are no leptons in the interaction, which is why they cannot be conserved. There are only baryons and mesons, which are made out of quarks. Lepton conservation, while correct, is irrelevant to this question because it doesn't involve leptons.
hope this helps