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Will this Reaction Scheme Go?

- NA -
(edited 10 years ago)
Original post by chemist90
Hi, Please could you look at my reaction and see if it is correct, the only thing I am not sure about is the use of tetrahydrofuran in the reaction.
If this wont proceed, could you please explain why and suggest an alternative, These given are the main reagents, chemicals and starting materials. I know how to use Magnesium Sulfate, DCM to extract, dry with MgSO4 etc. So I have not included them, just the primary reactions. Thank you for your help in advance and feedback. - The link is of the image of the reaction - http://www.tiikoni.com/tis/view/?id=031073f

WILL NEED TO ZOOM OUT :smile:


No, your reagent will react with itself..... Forms epoxide.

Use an epoxide to alkylate the OH, then halogenate the OH to get your product (PBr3)

Also any reason for that acid? Not the best acid if possible as it disproportionates very easily.
Reply 2
You need some sort of control when reactive your diamine with the halide to prevent double reaction. Also reductive amination could be more reliable.
OOH, didn't zoom out enough!

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