In general, my biggest weakness would be having the absolute lowest self esteem out of anyone, ever.
I wouldn't hold you to that, check out a recent AMA by a certain someone into Sherlock for some perspective. But still I'm sorry to hear you feel that way
______ My greatest weakness would probably be that I have high ideals for myself that I fear attaining so I deliberately self sabotage my potential for greatness and end up generally just a bit of an unemployed sleep deprived mess
ARRGH me scurvy sea monkeys me greatest weakness be walking onto me ship without me pegleg, that scurvy parrot bag steals it like a can of lard taking a monkey, me ships still in the arrghbour me mateys