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FSH and FOllicle maturation

Why does FSH not stimulate follicle maturaiton ALL the time? if FSH levels are always fairly high then one would think it would?
thanks
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Reply 2
I read maturation wrong :frown:
Reply 3
FSH levels aren't high all the time- matured follicles contain thecal cells which release androgens, which are then converted to estradiol (oestrogen) by granulosa cells (present in the follicle). Oestrogen at low concentrations inhibits the release of FSH from the pituitary, so the formation of the Graafian follicle essentially stops FSH production for a little while. Following ovulation, the corpus luteum releases progesterone which also inhibits the release of FSH from the pituitary (negative feedback). Follicles need a certain amount of FSH in order to mature- the level of which is too low throughout the majority of the menstrual cycle :smile:

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