Hey! Sign in to get help with your study questionsNew here? Join for free to post


Announcements Posted on
TSR's new app is coming! Sign up here to try it first >> 17-10-2016
    • Thread Starter

    Does anyone know where I can find good explanations about HIV infection and ELISA? I am really confused about the whole thing right now
    Thankyou so much

    HIV infection - blood based infection, high rates of mutation, ssRNA retrovirus - primarily infects T cells via binding of gp120 to CD4 + CXCR4/CCR5. ssRNA genome is converted to DNA via reverse transcriptase, then integrated into the host cell genome with integrase. This results in the production of a variety of regulatory proteins like Tat/Rev/Nef, followed by the formation of a new HIV particle, and its release from the host cell.

    ELISA is the detection method, where patient serum samples are tested for antibody (Ab) titers against HIV - indirect and competitive ELISAs are both used.
Write a reply…


Submit reply


Thanks for posting! You just need to create an account in order to submit the post
  1. this can't be left blank
    that username has been taken, please choose another Forgotten your password?
  2. this can't be left blank
    this email is already registered. Forgotten your password?
  3. this can't be left blank

    6 characters or longer with both numbers and letters is safer

  4. this can't be left empty
    your full birthday is required
  1. Oops, you need to agree to our Ts&Cs to register
  2. Slide to join now Processing…

Updated: May 11, 2016
TSR Support Team

We have a brilliant team of more than 60 Support Team members looking after discussions on The Student Room, helping to make it a fun, safe and useful place to hang out.

Do you like sleeping in a cold room?

The Student Room, Get Revising and Marked by Teachers are trading names of The Student Room Group Ltd.

Register Number: 04666380 (England and Wales), VAT No. 806 8067 22 Registered Office: International House, Queens Road, Brighton, BN1 3XE

Reputation gems: You get these gems as you gain rep from other members for making good contributions and giving helpful advice.