Depends what is meant by drastic, but simply put: yes.
A lot of his polcies are actually in step with tue congressional GOP meaning he will be able to do a lot. The things we hear (our media being brilliant at impartiality and all) probably won't, tje wall for inatance will be difficult to get past congress.
It's alsp worth noting that this is an important epectionf for the SCOTUS, and a Trump win would strengthen the Conservarive majority and make it last another few decades, which will have a major impact.