Nah not really, I applied to Cambridge, LSE, UCL, Nottingham, SOAS and Durham...Got offers from most of them with similar results. Predicted IB grade was 41 but got 43 in the end with:
HL: History, English, Geography and Biology
SL: Maths Methods and French
(SOAS gave me a 36 pt offer. LSE and Nottingham were 38 pts with 7, 6, 6 at higher. And Cam rejected.)