You'll have ABBB at AS? Yes that will put you at a slight disadvantage.... but it wont stop you getting in if you have a good PS and choose your choices carefully! There is a lot of information lurking around these forums pointing out what particular unis look for. If you do your research and apply to places that take an interest in your strengths, and avoid places that looks more closely at your weaknesses, then you can give yourself as good a chance as anybody.
Make sure your teachers give you the predicted grades you need, and do some retakes in January to boost yourself up a bit. It's certainly not over yet!