TB3 Lecture 2 Brain Development

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  • Created by: mint75
  • Created on: 25-04-15 19:01

1. What are the three stages (in order) of cellular development

  • Proliferation, cell migration, myelinisation
  • Synaptogenesis, Cell migration, proliferation
  • Myelinisation, Cell migration, proliferation
  • Synaptogenesis, Myelinisation, Cell migration
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2. What effects does the environment have on the prenatal brain?

  • The PN brain is sensitive to negative and positive influences, with cortical thickness differing according to the environment
  • The PN brain is especially sensitive to negative environmental influences affecting cortical thickness
  • The PN brain is especially sensitive to positive environmental influences affecting cortical thickness
  • The environment has not shown to have an effect on the PN brain

3. As the cortex grows, what happens to the brain?

  • Synaptogenesis occurs
  • Infolding to accommodate rapid growth
  • Synaptic pruning
  • Vesicles develop

4. What is the second stage of brain development?

  • Cell insulation
  • Folding of the neural plate to form the neural tube
  • Neurogenesis and cell migration
  • The formation of the hindbrain

5. What are the main characteristics of fetal alcohol syndrome?

  • Physical defects (e.g flat midface, microcephaly, micrognathia), growth retardation and CNS difficulties
  • Growth retardation (e.g low birth weight) and balance and hearing issues
  • CNS issues (e.g learning/behaviourla disorders), Growth retardation emotional disturbances and
  • Small hippo-campus and other physical defects (e.g flat midface, microcephaly, micrognathia)


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