Confidence is such an important factor when talking to the opposite sex. I was rarely confident, infact the last two girlfriends I had (one serious, one not so serious due to the length of the relationship) had either come to me and initiated things or were in a position where a relationship looked impossible and as such I treated it as nothing more than a friendship.
Since my last relationship i've not wanted to be with anyone else - I'm quite content being by myself and focussing on me and the changes in my life that I want to make to become the person I want to be. One of those changes is to be more confident, though, especially with the opposite sex, so have pushed myself to talk to more girls on nights out etc (though obviously without leading anyone on). It seems to have been a success, I get into engaging and interesting conversations quite regularly now and it's nice to know I can go up to women and spark up a nice conversation. I've admittedly had a couple of girls interested without trying to lead them on, but usually it's just chatting etc, so it's not as if i'm talking about engaging a girl i'm interested in. I can't imagine it's much different though, as in reality you'd not want to come off as too eager anyway.
Maybe spend some time on yourself to build your own confidence up and then if something comes along in the meantime, be open to it.