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A2 Biology OCR June 2015 Revision Thread

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Original post by frozo123
same here man, looks like we're working on the same wavelength haha
what course are you doing?


After A levels? Medicine

Just printed the bastards off
Original post by ChatteringJess
Does anyone understand the different gene therapies? please :smile:


I've literally just woken up from a 20 minute turned 2 hour nap so if this is jumbled then I'm sorry haha.

A gene therapy is a therapeutic technique where the functioning allele of a particular gene is placed in the cells of an individual lacking in the functioning alleles of that particular gene.

Somatic Cell Gene Therapy has two types:
Augmentation (adding genes) is where a faulty allele for a gene may lead to the organism being unable to synthesise an important protein. Augmentation is where a functioning copy of the gene is inserted, and the protein can now be synthesised.
Killing cells is where cancerous cells can be engineered to produce a particular protein (e.g cell surface antigens), causing an immune response. This may lead to a new way to treat cancer.
It must be repeated regularly as it is a short term treatment as the specialised cells containing the gene will not often divide to pass on the allele.
It is difficult to get the gene into the genome in a functioning state. Liposomes have been trialled to do this, as they are made from the same lipid bilayer as the cell membrane, and can therefore pass straight through. Genetically modified viruses have also been tried but the host becomes immune to them so the cell will not accept the vector on following treatments.

Germline Cell Gene Therapy
The germline cells are the sex cells, sperm and egg, but this therapy can also work for zygotes too.
The functioning allele is introduced into germline cells so all cells derived from the germline cells will have a copy of the functioning allele. This means the patient could potentially pass on this allele to their offspring.
This, however, is considered unethical in humans because there could be unintentional changes that may damage the embryo, it raises ethical issues of whether we should genetically engineer embryos, we could interfere with human evolution in ways we do not know.

If there's anything incorrect, feel free to correct me anyone. I hope this helps :smile:
(edited 9 years ago)
Original post by Solarburst
After A levels? Medicine

Just printed the bastards off


Haha same
and they're alright tbf
unit 5 is gonna be annoying to learn cbf
Original post by frozo123
Haha same
and they're alright tbf
unit 5 is gonna be annoying to learn cbf


When I said Unit 1 I meant F214 aha

Where are your offers from?

Is that ecosystems or some ****?
Original post by Solarburst
When I said Unit 1 I meant F214 aha

Where are your offers from?

Is that ecosystems or some ****?

yeah I got you aha
georges and UEA, wbu?

idek man I've been sleeping every lesson haha
Original post by frozo123
yeah I got you aha
georges and UEA, wbu?

idek man I've been sleeping every lesson haha


Exactly the same offers aha, waiting on Bristol

Learning all this **** myself because my lessons are crap, story of my exam life
Original post by Solarburst
Exactly the same offers aha, waiting on Bristol

Learning all this **** myself because my lessons are crap, story of my exam life


ah where you picking over them two? or three if you get that,
yeah think a lot of people doing Biology are in the same situation
Original post by frozo123
ah where you picking over them two? or three if you get that,
yeah think a lot of people doing Biology are in the same situation


It's not just bio, my chem teachers are worse :/

Debatable between UEA and Bristol

I think George's is out of the question because there's only medical related professions and the area isn't too great, even though the hospital is great
Original post by frozo123
ah where you picking over them two? or three if you get that,
yeah think a lot of people doing Biology are in the same situation


You?
Original post by Solarburst
You?


Yep picking UEA, the area is scum in Tooting
Original post by frozo123
Yep picking UEA, the area is scum in Tooting


phahaha brutal but honest

Anyway back to starting these past papers,

gl with everything, possibly see you at UEA next year :smile:
Original post by Solarburst
It's not just bio, my chem teachers are worse :/

Debatable between UEA and Bristol

I think George's is out of the question because there's only medical related professions and the area isn't too great, even though the hospital is great


I would definitely firm bristol and put insurance as UEA. Bristol has much better student life trust me!
Original post by phoebc
I would definitely firm bristol and put insurance as UEA. Bristol has much better student life trust me!


are you insinuating the UEA nightlife is ****?
Original post by phoebc
I would definitely firm bristol and put insurance as UEA. Bristol has much better student life trust me!


Waiting on Bristol, I think I'm on the 'on hold' part and they're waiting to see how many firm etc before the give out more offers :/

How can you compare the two?
Original post by Solarburst
Waiting on Bristol, I think I'm on the 'on hold' part and they're waiting to see how many firm etc before the give out more offers :/

How can you compare the two?


I have cousins who are at both unis and have stayed with them both. Even though UEA is still a good uni and does have good student life. When staying with my cousin in Bristol compared to staying with my cousin at UEA, I had a much better time at Bristol
Original post by phoebc
I have cousins who are at both unis and have stayed with them both. Even though UEA is still a good uni and does have good student life. When staying with my cousin in Bristol compared to staying with my cousin at UEA, I had a much better time at Bristol


Ok fair enough! Note taken, but I have to get an offer first and that's looking unlikely aha
Original post by Solarburst
phahaha brutal but honest

Anyway back to starting these past papers,

gl with everything, possibly see you at UEA next year :smile:


ye you too man gl with Bristol
Hey guys. I was just wondering. How far is everyone with revision for F214 and F215?
Original post by CountessDracula
Hey guys. I was just wondering. How far is everyone with revision for F214 and F215?


I've made all and double sided nearly all of my flashcards for both modules. I'm now in the process of making more detailed notes to learn from :smile:

How about you?
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Original post by CountessDracula
Hey guys. I was just wondering. How far is everyone with revision for F214 and F215?


F215 is so painfully long.

Too much on plants, and animal responses ughhh

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