I just don't really think Hitman is suited for the big screen. To be 100% faithful, it would probably be too disjointed and slow-paced for the people who go see it (even fans, as they don't have the immersive aspect of controlling him). I think the best way to go about it would be a mixture of Mission Impossible and Bourne - show the raw, physical fighting aspects of the Bourne movies, but with less shaky cam and gritty realism, and more high-end flashiness that is associated with Mission Impossible.Oh, and Shooter (Mark Wahlberg), which shows the methodical nature of assassinations, and is one of my favourite action movies.
You know what's going to be amazing? Assassin's Creed. The trailers for Macbeth so far have blown me away, with some of the best style and cinematography I have seen for years. With a loyal and well-designed script, I have faith Assassin's Creed can be the video game adaptation we have been waiting for.