Depends on what your predicted grades will be, I had BBDD AS, predicted BBB at A-Level (300 Ucas).
I ended up with CCE A-Level but still got on the course I wanted at Huddersfield, studying psychology, but I had applied for law and changed last minute.
So all depends really! Go off your predicted grades and apply anywhere, but don't forget to always apply for a foundation course. I applied for the foundation course at Manchester Met at 200 UCAS and the actual course is 300 UCAS. That is a good Uni. So is Huddersfield, for 300 Ucas.