is "pre-u global perspectives respected?"
if it's what I think it is, a general studies/critical thinking kind of subject, probably not. Chances are it won't be ignored on your uni application but it probs won't form part of any offer, I think.
in terms of facilitating subjects, it could be that yes, you need one for a uni application. they do look good and present you as academic, but, I've always maintained that you shouldn't do them for the sake of it.
Getting an A in a non-facilitating subject is better than getting an E in a facilitating subject.
If you think you can do well in them (fac subjects) with hard work etc then it's better to go for them imo since it can open a range of doors/possibilities at uni.
EDIT; I did 4 proper AS subjects + general studies,although I started in 2015 when the reform had only just begun. I know that at my 6th form from the year after (2016 September) you could only do 3 AS subjects, which leaves no room to drop one for yr13, so if this is the case for you, think very carefully about what you want.