Advantages: people don't bother you/talk to you in the middle of lectures, you can sit where you want, usually easier to concentrate in general
Disadvantages: group work/lab work a lot of the time you have to choose groups yourself, and it can be awkward when you're on your own. Lots of field work on my course but I usually do it alone whenever possible and I prefer it like this. Sometimes there'll be other people without partners/groups and they'll approach you asking if they can work with you. A few times I've said "sorry I'm just working on my own" and then not realised that it was probably a bit rude. So another disadvantage is that other people probably think you're being anti social, when you just prefer to do things alone.
Last one I can think of is not having many people to discuss assessments/exams with, but in 1st year when I was more social I noticed most people end up doing the work at the last minute, and there's usually one person in the group who they all turn to a week before the deadline (that person was me), so I didn't gain much from speaking to people about work anyway. I'm not sure how it is with other students but my experience is that most people either don't know the content or don't want to help you/anyone anyway.
So my advice is to just pay as much attention as you can, make sure you interact with the lecturer (I usually sit at the front so I can do this easily) and still try to be friendly or give a smile when someone sits next to you, because you might end up needing to work in a group one day.