Why on Earth would you want to carry a heavy handbag around, which probably won't fit all your stuff in anyway? Literally nobody took a handbag to my college, everyone took a backpack instead.
You're better off just getting a backpack; they're practical, have enough room for everything, and you can comfortably carry things around.
Seriously, don't prioritise style at college - it's what's in the bag that counts, not what the bag looks like.