if you're a mature student i.e. over 21 at the start of the course, unis will often be more relaxed about grades if you've gained relevant experience.
they often put a requirement in about successfully achieving something in education in the last few years... but they don't tend to relax the requirement for maths and english gcse (or equivalent) so you'll probably need to already have C/4 in those.
best path is to enquire with the unis you're interested in