I currently live in a city, and would rather live in a village or a small town like I used to. It's so much better when there are fewer cars on the road and hopefully nothing to ruin the beautiful scenery or mug you during your daily business.
Isolation is no problem whatsoever, in fact it's much preferred. As long as there is a decent supermarket within five or six miles, you can get all the essentials you need with relative convenience.