Codeine not working Watch

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beepbeeprichie
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#21
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#21
(Original post by Dumachi)
Well what type of pain are you suffering from?


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knee pain
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2007PSanHa
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#22
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#22
I watched something today that said that codeine doesn't have any effect in some people!
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InArduisFouette
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#23
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(Original post by beepbeeprichie)
No. Paracetamol never did anything for the pain.
WHO analgesic ladder time

Paracetamol + NSAID (assuming no contraindications ) +Codeine is a fairly decent combination

However, if you are just taking 30mg of codeine alone for moderate to severe pain it's unsuprising it's not that effective.

Nausea with opiates can also come from the slowing of the digestive tract associated with taking them, which is why advice should be given if you are going tpo be taking them for more than couple of days along with the consideration of macrogols or lactulose to prevent total log jam.


different people have different proprtions of the different opiate receptors which means different opiates work better forsome people than others ( tramadfol is one of the most common ones for very variable effects )

very simplistic description of the ladder

http://pda.rnao.ca/content/managemen...algesic-ladder

note that none opiate and adjuvants ( which includes the NSAIDs) feature at all three stages and underpin effective analgesia prescribing.
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InArduisFouette
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#24
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#24
(Original post by 2007PSanHa)
I watched something today that said that codeine doesn't have any effect in some people!
There are a number of different opiate receptors and different people have different proportions of them. Different opiate drugs have differing proprtions of things to fit on to each type receptors, so if you care given a drug that mainly wants to latch onto a type of receptor you don't have many of it won't work for you ...
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User1634027
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#25
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#25
(Original post by zippyRN)

very simplistic description of the ladder

http://pda.rnao.ca/content/managemen...algesic-ladder
Lol @ Implying the ladder is complex
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Icecream1
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#26
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#26
(Original post by beepbeeprichie)
I've been prescribed codeine for pain management but it doesn't work at all.

It just makes me feel kind of drunk.

Why is it not working?
Codeine works by being converted to morphine in the liver, if your enzymes are not good at converting it, you get no therapeutic effect.

Go back and see your GP and he/she should swap it to something more suitable.
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455409
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#27
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You need to take codeine alongside paracetamol and ibuprofen, or it won't work very well at all. The two individually do very little but taken together they increase each other's effects.

Failing that it's time to go back to the doctors and move onto Tramadol.
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Kabloomybuzz
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#28
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#28
(Original post by beepbeeprichie)
knee pain
Knee pain can be caused by a wide range of things, so you can't really say its well documented that analgesics and anti inflamaatories don't work. On the contrary, anti inflamatories tend to work very well on general joint pain. If one or the other aren't working, perhaps try taking them together. or taking one or the other with codeine. I say this as someone who has had knee problems since childhood (caused by maltracking of the patella - my kneecap moves more than it should)

It might also help a little to take something like cod liver oil capsules, as its well known to be good for joint problems, or use a knee support bandage/wrap.

If/when you've tried a few things and nothing is honestly working, then you need to ask your doctor to do further investigations such as blood tests and referrals to a specialist (probably rheumatology) and/or a physiotherapist to work out whats actually causing the pain and the best way to treat/deal with it. It may be that nothing will make the problem much better, and the best you can do is identify what makes it worse and minimise it.

You don't want to be taking codeine long term anyway as it can be addictive.
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iJess
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#29
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I have hypermobility and dislocated my patella and I was on co-codamol ad well as some anti-inflamattory gel. its got ibupurofen in the gel. I cant take ibupurofen normally as it makes me wheeze but im fine with the gel it was called voltarol. ask your gp if they can prescribe some, it actually worked with the pain and swelling for me, alongside co-codamol.
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moonkatt
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I'm closing this thread before any more dangerous advice can be given. You've been given some sensible advice here OP, I'd suggest you go back to the doctor who has prescribed you the codeine for further advice or speak to your pharmacist.
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