Pretty good but depends what you like.
I generally did Anglia Ruskin student night on Mondays at Life, until they stopped doing it, so I went to Cindies instead. Pop and commercial R&B and dance. Also did Cindies Tuesday a lot, basically the same as Cindies Monday but a bit more cheese and it's a student night so it's full of students rather than locals. Wednesday I either did Cindies again (a lot of cheese) or International Night at Fez (hip-hop, R&B, dance, bollywood, eurodance etc). Thursday night was Secret Disco night (was at Soul Tree, is now at Life...70s, 80s and 90s). Friday night Wetherspoons is brilliant, and Soul Tree or Kambar after it shuts (it shuts at 2am whereas Soul Tree and Kambar go on a bit later). I didn't usually go out on Saturday but if I did I'd repeat Friday night. Sunday night I used to go to Life, massive student night...a lot of cheese and commercial music again.
The most popular events seem to be Monday at Fez (Fat Poppadaddy's...overrated imo but people seem to enjoy it), Tuesday/Wednesday Cindies and Sunday at Life. My personal favourites were Monday Cindies, Friday Wetherspoons and Sunday Life. There are loads of specific nights e.g. 'ghetto' night at Fez which is pure hip-hop and R&B, pretty good, and loads of DNB/psytrance/dubstep nights in King's cellars. If you're willing to go further afield there is The Junction which has a few club nights. And I always forget Revolutions, that's quite fun too.