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    In question 3c)a)i) on this paper:

    http://docs.google.com/viewer?a=v&q=...iqBx61dI9xRhZA

    What do you do with the proline to form that peptide bond?
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    It's the same as the other except instead of NH2 you have NHR

    So you end up with a secondary amide instead of a primary amide.
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    Yeah but I don't get what happens to the ch2ch2ch2 group when the amide group is formed. Can't the nitrogen atom only have three bonds? Or am I being stupid actually thinking about it, so do you just attach the carbonyl group to the NHR group and have the four groups around the nitrogen atom?
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    Remeber that H2O is removed - the OH from the COOH and the H from the NHR, so you'll end up with three N-C bonds :yep:
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    Oh right! I get it now, thanks. You have to produce one water molecule from the formation of each peptide bond! That'll help me with future questions, thanks.
 
 
 
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