tried starting up in safe mode?
When you download the removal tool for it, save it as a different name. Sometimes the virus/spyware blocks certain removal programs.
Try my other solution as well, the removal program should work.
Are you using Spyware doctor?
The virus has damaged your file extension information. For example, a .doc file will be registered with microsoft word. It seems the .exe extension is messed up, it can happen due to certain malware. I gotta go uni, but will try to find a fix when I get back.
Force the computer to shut down, do so by holding the power key for about ten seconds, it should then give you the option to start normally, in safe mode with command prompt or in safe mode with networking. Do the latter, and then run your AV and try again to download spyware and malware software.
What operating system is it? Windows Xp / vista / 7 / other?
If F8 isn't working to give you the option to load safe mode, chances are USB keyboard shortcuts are disabled in your BIOS. so enable them.
Or you could connect an old PS/2 keyboard.