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How does genetic engineering create insulin for diabetics?!!! watch

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    Hey so im tryin to find out how genetic engineering works to create insulin, can anyone please talk me through it step by step, i have looked on the internet but cant find anything that makes much sense? If u hav any sources please post the link as well. THANKS!
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    LMGTFY
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    (Original post by G8D)
    They take a bacteria.
    The remove the "plasmid", this is the unnecessary-to-life piece of data/xNA.
    They then isolate the useful gene (in this case the one that makes insulin) from human DNA and "splice" it into the plasmid using enzymes.
    The plasmid is then inserted back into its bacterial cell and if it works it will replicate and start producing masses of human insulin, non of that crappy pig stuff.
    This, and then I get to live. Yay, not crappy pig insulin!
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    So where does the human DNA come from? they take cells from the person with diabetes?
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    (Original post by Feebz)
    So where does the human DNA come from? they take cells from the person with diabetes?
    Yes. Diabetic cells are very useful apparently.
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    (Original post by Feebz)
    So where does the human DNA come from? they take cells from the person with diabetes?
    No, from healthy people, as the people with diabetes do not have insulin, hence the problem of diabetes
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    (Original post by Feebz)
    So where does the human DNA come from? they take cells from the person with diabetes?
    From a person with a functional insulin gene.
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    How do they get the gene from the healthy person?
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    (Original post by Feebz)
    How do they get the gene from the healthy person?
    I think it's just obtained from a blood sample from a non-diabetic person... I could be wrong on that though, I'm no specialist!
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    (Original post by Sprockette)
    I think it's just obtained from a blood sample from a non-diabetic person... I could be wrong on that though, I'm no specialist!
    i think its from the pancreatic cells or wherever insulin is produced.
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    (Original post by obviouslystudying)
    i think its from the pancreatic cells or wherever insulin is produced.
    I thought that was if you want to get the actual Langerhan cells? With DNA can you not get it from blood and isolate the gene? I can't seem to find it yet online anywhere.

    As I said above though, I don't know anything really, I'm just curiously questioning!
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    I'm back to correct myself, you do have to obtain human insulin producing cells!: "Human insulin producing cells are extracted to obtain the functional genome (the genetic material which determines the capacity of the cells to produce insulin) which is used to transform fungal cells, making them capable of producing insulin."
 
 
 
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