Functions of glycoproteins in the plasma membrane

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Sanchez Amirez
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#1
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#1
Membranes contain a variety of proteins. Some of these proteins are combined with carbohydrates to form glycoproteins.
Describe the functions of glcycoproteins in the cell surface membrane?
(5 marks)

help please :confused:
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ciawhobat
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what level of education is this at?
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Sanchez Amirez
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AS-level biology OCR
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Flo_Ryder89
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If I vaguely remember;

They help stabilise the membrane structure by forming hydrogen bonds with the water molecules in the surrounding fluid.

They also act as receptor molecules by binding with particular substances

hope this helps a little
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ciawhobat
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erm, for AS level haha... erm, best just read your syllabus off the OCR website?
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atheistwithfaith
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#6
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#6
Presuming we are just talking about glycoproteins and not proteoglycans...

Cell:cell recognition / interaction
Structural components
Transport
Immunity
Hormonal / Metabolic

Not strictly membrane functions:
Lubricants + shock absorbers
Antifreeze (in arctic fish)
Protein folding

Pretty important things those glycoproteins.
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joshed
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#7
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(Original post by atheistwithfaith)
Presuming we are just talking about glycoproteins and not proteoglycans...

Cell:cell recognition / interaction
Structural components
Transport
Immunity
Hormonal / Metabolic

Not strictly membrane functions:
Lubricants + shock absorbers
Antifreeze (in arctic fish)
Protein folding

Pretty important things those glycoproteins.

glycoproteins and proteoglycans are the same thing :p:

glycoproteins can also be used for cell to cell recognition, in the immune system.

On another similar note glycoproteins can be used as drug targets in drug design.
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Revd. Mike
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(Original post by joshed)
glycoproteins and proteoglycans are the same thing :p:

glycoproteins can also be used for cell to cell recognition, in the immune system.

On another similar note glycoproteins can be used as drug targets in drug design.
Proteoglycans are glycoproteins, but not all glycoproteins are proteoglycans They're not interchangeable.
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joshed
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(Original post by Revd. Mike)
Proteoglycans are glycoproteins, but not all glycoproteins are proteoglycans They're not interchangeable.
How is that? What could be classed as a glycoprotein and not a proteoglycan?
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atheistwithfaith
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#10
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(Original post by joshed)
How is that? What could be classed as a glycoprotein and not a proteoglycan?
Proteoglycans usually have a much more structural role, they have a carbohydrate composition of up to 97% whereas glycoproteins have a composition of between 1-60% (generally).

The main differences is that a glycoprotein is usually a protein with carbohydrate attached to certain recognition sites, whereas a proteoglycan has a protein at its core and is then completely covered with a highly charged type of carbohydrates called glycosaminoglycans.
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Revd. Mike
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^Precisely that
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joshed
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#12
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(Original post by atheistwithfaith)
Proteoglycans usually have a much more structural role, they have a carbohydrate composition of up to 97% whereas glycoproteins have a composition of between 1-60% (generally).

The main differences is that a glycoprotein is usually a protein with carbohydrate attached to certain recognition sites, whereas a proteoglycan has a protein at its core and is then completely covered with a highly charged type of carbohydrates called glycosaminoglycans.
Excellent, thank you for clearing that up. Guess thats what happens when you let an organic chemist teach you about proteins :P

The wonders of Biochemistry I guess :P:
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Unicorn15
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#13
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#13
the act as receptors and bind to complementary glycoprotiens for cell communication
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