Don't worry in some ways I had the same fears when I didnt go to my schools sixth form this year instead college youll make friends with people who are in your classes it just happens.
Just relax, you'll make friends in classes.
Just make sure they like you back, we spent quite a while "hinting" at this guy that he wasn't a good fit on our group before he left, after a year.
He was resilient.
Try and stand out the first day, not in a weird way though. In this world first impressions are made on looks and confidence, so don't knock your chances right at the start. Do your hair the way you know it looks nicest, maybe put good mascara to highlight your eyes, wear something you look good in (for eg. If you have good legs wear a good pair of jeans or leggings). But most importantly, be confident. Walk like you know where you're going, don't look down, ask the people you sit next to what their name is at the start of each class. Most people don't know you so if they see a presentable confident girl who greets them with a smile they'll automatically have respect for you
Me and the science department get along fine
I didnt know anybody either when i first started but quickly made alot of new friends. The teachers held games/quizzes/competitions to get everyone talking for the first week which helped everyone a lot.
I was very shy for the first couple of days, but then opened up alot more since everyone started getting to know one another more during the games. Then you will find out that some of the other classmates have the same thing in common as you and then you will become friends and hopefully have a great first year in college.