Went to Ministry last night- it was the launch party for their new 'Switch' clubnight- saw Groove Armada; twas excellent.
Fabric is cool on Friday nights- drum and bass, hip hop, breaks etc... prepare for a long queue tho.
On Mondays check out Trash @ The End if your into indie etc...Saw Soulwax there last Monday- immense!
Cargo in Shoreditch is another goodun.