Biology help needed please! Watch

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wigman15
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Hey!

How do lymphocytes get to the sites of infection from the lymph nodes?

Thanks
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GH
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(Original post by wigman15)
Hey!

How do lymphocytes get to the sites of infection from the lymph nodes?

Thanks
They utilize specialized surface proteins and carbohydrate entities called adhesion molecules for trafficking through the host. These adhesion molecules recognize specific ligands on endothelial cells of the vasculature and the secondary lymphoid organs allowing them to bind and cross through the endothelial cell barriers.
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wigman15
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(Original post by 2776 2)
They utilize specialized surface proteins and carbohydrate entities called adhesion molecules for trafficking through the host. These adhesion molecules recognize specific ligands on endothelial cells of the vasculature and the secondary lymphoid organs allowing them to bind and cross through the endothelial cell barriers.
Thank you very much for your help. Unfortunately, I do not understand most of that as I am an AS student and haven't done much detail about lymphocytes at school.
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GH
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(Original post by wigman15)
Thank you very much for your help. Unfortunately, I do not understand most of that as I am an AS student and haven't done much detail about lymphocytes at school.
Same here. You can surely understand some of it, ie carrier proteins etc...
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wigman15
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(Original post by 2776 2)
Same here. You can surely understand some of it, ie carrier proteins etc...
I understand that bit, but what does this mean "specific ligands on endothelial cells of the vasculature and the secondary lymphoid organs"?
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GH
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(Original post by wigman15)
I understand that bit, but what does this mean "specific ligands on endothelial cells of the vasculature and the secondary lymphoid organs"?
Ligands are like water ligands on berilium. Similar to glycoproteins in shape and function.

Endothelial cells are cells in the inside of the blood vessel

Vasculature-mass transport system of body, ie blood vessel


2ndry lymphoid organs = control the quality of immune responses. There are Differences among the various lymphatic tissues, this is the secondary one
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nikkij1
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Go onto the s-cool site. its really good for all that and it should tell ya. what exam board r u doin bio with??
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cipapfatso
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If it helps, a ligand is where a molecule contains a metal atom(s) which is bonded to non-metal atoms by means of dative covalent bonds.
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