TheWonderKid
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Hi, this is in the CGP revision guide but i don't quite understand what it means.

It says,

Emphysema is a lung disease caused by smoking or long-term exposure to air pollution--foreign particles in the smoke (or air) become trapped in the alveoli.

This causes inflammation, which attracts phagocytes to the area....


I dont quite fully understand the "This causes inflammation" bit. Coulkd someone explain please? cheers
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16ARTER
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In normal breathing, air is drawn in through the bronchi and into the alveoli, which are tiny sacs surrounded by capillaries. Alveoli absorb oxygen and then transfer it into the blood. When toxicants, such as cigarette smoke, are breathed into the lungs, the harmful particles become trapped in the alveoli, causing a localized inflammatory response. Chemicals released during the inflammatory response (e.g., elastase) can eventually cause the alveolar septum to disintegrate and attracts the phagocytes as they have been stimulated by the chemicals released.

Hope this helps!
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TheWonderKid
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Report Thread starter 8 years ago
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(Original post by 16ARTER)
In normal breathing, air is drawn in through the bronchi and into the alveoli, which are tiny sacs surrounded by capillaries. Alveoli absorb oxygen and then transfer it into the blood. When toxicants, such as cigarette smoke, are breathed into the lungs, the harmful particles become trapped in the alveoli, causing a localized inflammatory response. Chemicals released during the inflammatory response (e.g., elastase) can eventually cause the alveolar septum to disintegrate and attracts the phagocytes as they have been stimulated by the chemicals released.

Hope this helps!
Thankyou!
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nexttime
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Inflammation is a huge topic in itself, although you only really need to know its name, i think! Its basically about how the local cells communicate to other cells that they have been damaged. This is vital to start wound repair, or in fighting off infections, and involves a huge number of processes that allow the immune system to function. Chronic inflammation can result in long-term changes to the cell structure, as in some scars or emphysema.
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