FOP (Fibrodysplasia ossificans progressiva) Watch

16ARTER
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#1
Report Thread starter 8 years ago
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Hi, i need some information on how FOP is related to BMP-4 and some background information on FOP please!
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nexttime
  • Volunteer Team
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Report 8 years ago
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Try wikipedia/Pubmed. If you have anything you don't understand then feel free to ask.
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misfit1993
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(Original post by 16ARTER)
Hi, i need some information on how FOP is related to BMP-4 and some background information on FOP please!
FOP, A genetically inherited condition, which causes the growth of bones where they shouldnt be, it is very rare.
BMP- Bone morphogenic protein (there is a whole family of them) but from what ive read about FOP when damage occurs in the body the white blood cells rush to the area in an inflammatory response. The white blood cells then express this bone morphogenic protein which they shouldnt (i think this is because of gene expression going wrong and the gene not been switched off) which then diffuses into surrounding cells causing them to differentiate and become specialised bone cells.
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16ARTER
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Report Thread starter 8 years ago
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thanks
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