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    Use your knowledge of the structure of a neurone to explain why many neural toxins and poisons work at the synapses, rather than along the length of the neurone.
    I've looked at this from every angle I can think of, yet I can't relate the structure of a neurone to why the synapse is attacked more than the axon of the neurone itself.

    Any clues or ideas?
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    My best idea is that toxins and poisons can access the synaptic cleft easier, because its filled with fluid and not actually inside a neurone. And that the axon is covered in myelin sheath which provides protection. Please quote me if I'm wrong, I love studying this and would love to know if I'm making mistakes.
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    you're not thinking about it the right way.

    #consider the mechanism by which action potentials are converted to chemical neurotransmission. each stage represents a potential target for a toxin. compare that to the different stages of the action potential that can be targeted. the difference is massive!
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    Take a look at how botulinum and tetanus toxins prevents the SNARE complex from forming and it's subsequent impact on priming and neurotransmission. Or, more specifically, identify what it is about the synapse which allows the toxins to enter the cytoplasm. What happens to the membrane here that the toxins can take advantage of?
 
 
 
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