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AQA BIOL5 Biology Unit 5 Exam - 22nd June 2011

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If I pass this exam it's going to be thanks to you guys for getting me through this, seriously!
Original post by aj2010
Just wondering, I though for A* you had to get over 90 ums in unit 4, over 126 ums in unit 5 and an A in As? :smile:


It is a 90% average in the A2 modules (unit 4,5,6) hence you need 270/300 for A2
and 480/600 ums for your overall A Level
Original post by Carpet21
The book doesn't really tell us much about troponin does it?


The NT book? Nope. :p: I only know about tropomyosin really. =/
I'm really struggling with keeping resting/action potentials straight in my head, i keep forgetting when which gates open :/ does anybody know how to remember something so long and complex?
Reply 1744
Original post by Tericon
Histamines must be released when allergens enter the body as allergy medication contains 'antihistamines'.

They both contribute to the inflammatory response however.


Thats what my originally thought too, but the CGP definitions are:


Histamine is a chemical mediator thats stored in mast cells and basophils. It's released in response to the body being injured or infected. It increases the permeabilty of nearby capillaries to allow more immune system cells to move out the blood to the infected area


Prostaglandins are a group of chemical mediators produced by most cells in the body. They're involved in things such as immflamation, fever, blood pressure regulation and blood clotting

Which is the other way round to what the other poster put I believe
(edited 12 years ago)
Do we really need to know how DNA are introduced to host cells? When plasmids get mixed together in a medium with calcium cells and all that? =/
Original post by Stirlo
Thats what my originally thought too, but the CGP definitions are:


Histamine is a chemical mediator thats soted in mast cells and basophils. It's released in response to the body being injured or infected. It increases the permeabilty of nearby capillaries to allow more immune system cells to move out the blood to the infected area


Prostaglandins are a group of chemical mediators produced by most cells in the body. They're involved in things such as immflamation, fever, blood pressure regulation and blood clotting


****! NT says this! Also googled this and Histamine is for allergies.
Original post by Sparkly-Star
Do we really need to know how DNA are introduced to host cells? When plasmids get mixed together in a medium with calcium cells and all that? =/


yep. :smile: and replica plating and stuff.
Reply 1748
Original post by Sparkly-Star
Do we really need to know how DNA are introduced to host cells? When plasmids get mixed together in a medium with calcium cells and all that? =/


Yeh I think you need to know about both the heat shock, (ice cold calcium chloride solution heated quickly to ~40) and about adenoviruses (Inject their plasmids into a cell along with restriction enzymes)
(edited 12 years ago)
Reply 1749
Original post by yellowpurpleyellow
I'm really struggling with keeping resting/action potentials straight in my head, i keep forgetting when which gates open :/ does anybody know how to remember something so long and complex?


You need to take notes, read them, cover them up, rewrite. Keep doing this until you make no mistakes.

Its the only way i can revise long winded chunks of Biology like that.
Why is atpase required in muscles? If it for the myosin head to return to it's original position andd to detach the cross bridges or is 'atp' used for that as an energy source?!?!?!
Reply 1751
Original post by Nadine2010
Why is atpase required in muscles? If it for the myosin head to return to it's original position andd to detach the cross bridges or is 'atp' used for that as an energy source?!?!?!


ATP is used for both providing energy for the 'rowing action' to occur and for the breaking of the acting-myosin cross bridges. SOrry posted too soon. ATPase is used as the enzyme which causes the breakdown of the ATP into ADP and Pi
(edited 12 years ago)
Reply 1752
Original post by Nadine2010
Why is atpase required in muscles? If it for the myosin head to return to it's original position andd to detach the cross bridges or is 'atp' used for that as an energy source?!?!?!



ATPase is an enzyme that catalyses the breakdown of ATP into ADP and inorganic phosphate, this reaction produces the energy (from atp) which is used to break the cross bridges, move the myosin head and to actively transport calcium ions back into the sarcoplasmic reticulum once muscle is no longer being stimulated by neurone.

Without ATPase, ATP cannot be broken down and so does not act as an energy source.
Reply 1753
hey, just to check, in muscles there is actin in the I bands, actin and myosin overlapping in the a bands and just myosin in the h zone?
Original post by Tericon
You need to take notes, read them, cover them up, rewrite. Keep doing this until you make no mistakes.

Its the only way i can revise long winded chunks of Biology like that.


Ooo i'll have to keep at it i guess... It's just so frustrating!!!

Thanks :smile:
Are you guys revising Unit 5 stuff or synoptic atm?
Reply 1756
Original post by jamesl1
hey, just to check, in muscles there is actin in the I bands, actin and myosin overlapping in the a bands and just myosin in the h zone?


The A band consists of the entire area where myosin filaments are present not just actin and myosin. WHich is why upon contraction the A band width stays the same as the myosin filaments don't contract. You're right with the other 2 though
Reply 1757
Original post by jamesl1
hey, just to check, in muscles there is actin in the I bands, actin and myosin overlapping in the a bands and just myosin in the h zone?


Yes :smile:

Two others:

M-line = middle of H zone, so just myosin

Z-line = marks boundaries of sarcomere

I remember AIH

A bands stay same length during contraction, I bands get shorter, H zone gets shorter. As does sarcomere.
I'm totally unprepared for this exam! Can't wait for tomorrow morning to be over..
Reply 1759
Original post by Stirlo
The A band consists of the entire area where myosin filaments are present not just actin and myosin. WHich is why upon contraction the A band width stays the same as the myosin filaments don't contract. You're right with the other 2 though


Thanks, that sounds like a potential nasty question, didn't know that, CGP just says A = actin and myosin.

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