B-Cell Migration from Bone MarrowWatch this thread
How do mature B cells get out of the bone once they are ready to leave? Do they travel out though a blood stream in the femur?
Lymphocytes are not motile like granulocytes or macrophages, and they enter the circulation through lymphatic channels that drain into the venous system of the blood.
Some lymphocytes leave and reenter the circulation, surviving for many years. You can find them in large numbers in the lymph nodes, tonsils, thymus, spleen and lymphoid tissue of the gastrointestinal tract.
You can try googling it or looking in any microbiology/immunology text book as well.