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functions of the crypts of lieberkuhn?

amylou

1

books aren't helping me very much, they are really vague!all they say is that these crypts secrete intestinal juice.

Reply 1

Stranded

11

well they do...I guess thats the function....

Reply 2

Madprof

12

Your textbook is correct, but in a bit more depth, crypts of Lieberkuhn have several functions:

1. Secret inactivated pepsin
2. Secret Hydrochloric acid (to lower pH and activate pepsin)
3. Secret mucus (to protect epithelial cells)

The inactivated pepsin is secreted at the bottom of the crypt, and is activated by hydrochloric acid, which is secreted at the top. This is to prevent the cells lining the crypt from being digested by the pepsin. The cells towards the top of the crypt are protected by a coating of mucus.

Reply 3

-Kav-

12

And, of course, to have the most bizarre name in Biology. :smile:

Reply 4

kartik45

You are wrong.
These occur in stomach.
LOL

You are wrong

Will someone tell me the correct function of crypts of lieberkunh?

Reply 7

Pafoster10

Crypts of Liberkuhs secrete large amounts of extracellular fluid (water-like) to convert the chyme entering the small intestines into a less viscous substance. This increases interaction between the enzymes of mucosal lining cells and the chyme. Therefore, necessary for adequate digestion and absorption of nutrients. Paneth Cells are common here to release anti microbial substances.

Patrick Foster

Biology Major at University of Louisiana at Lafayette.

Reply 8

jebw92

1

Hey, Patrick, you're an idiot.

They're in the small intestine. They contain lysozymes and eosinophilic granules.

James EB

Medical Student - USA

Reply 9

ozmo19

16

Original post by jebw92

Hey, Patrick, you're an idiot.

They're in the small intestine. They contain lysozymes and eosinophilic granules.

James EB

Medical Student - USA

BEST POST EVER haha :tongue:

Reply 10

Pinkberry_y

19

Original post by Madprof

Your textbook is correct, but in a bit more depth, crypts of Lieberkuhn have several functions:

1. Secret inactivated pepsin
2. Secret Hydrochloric acid (to lower pH and activate pepsin)
3. Secret mucus (to protect epithelial cells)

The inactivated pepsin is secreted at the bottom of the crypt, and is activated by hydrochloric acid, which is secreted at the top. This is to prevent the cells lining the crypt from being digested by the pepsin. The cells towards the top of the crypt are protected by a coating of mucus.

All the things you're talking about happen in the stomach, not function of crypts of lierberkuhn :s-smilie:

Reply 11

icreatedthisjust

Crypts of L secrets enteropeptidase which plays a major role in the initial activation trypsinogen to trypsin. From then on its a cascade reaction because other digestive hormones require the activation from trypsin including other activation of trypsinogen. For example trypsinogen-(activation by trypsin)->trypsin can cleave Arganine and Lysine, chymotrypsinigen-(activation by trypsin)-> chymotrypsin can cleave the aromatic amino acids, proelastase-( activation by trypsin)-> elastase can cleave glycine, alanine ,and serine. And finally, procarboxylase -(activation by trypsin)-> carboxylase can cleave the amino acid at the end of carboxy group of the peptide. All these happens at the small intestine and its stimulated by CCK ( this is made by your APUD cells)

med student

(edited 8 years ago)

Reply 12

icreatedthisjust

fyi, correct me if im wrong.

(edited 8 years ago)

Reply 13

freddie-greswold

1

this is gastric glands in the gastric pits of the stomach, and not the crypts of Lieberkuhn which are in the small intestine