I've been prescribed prednisolone (and before that had injections of methylprednisolone that should run out in a few days). Every single UK source I can find states "there are no known interactions between alcohol and Prednisolone" and the doctors, pharmacist or nurses didn't mention anything about alcohol so I decided I'd be fine to drink. When I did I ended up getting really drunk on a relatively small amount of alcohol. Looking at sources from other nations "Avoid drinking alcohol while you are taking methylprednisolone." comes up a lot but with no expansion on why or what happens. Does it effect your Liver, kidney and lungs (and any other organs responsible for eliminating alcohol down or breaking it down into acetic acid)?
I'm also on a few other medicines but I've drunk whilst having those before now and been normal so I'm assuming if it is because of a medication it's one of those or a combination.
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