I live in Warrington. It isn't rough, on the whole. The area around the campus is quite nice, it's very residential though. It's also about 3 miles from the town centre, about £10 at night for a taxi. The halls look quite rough too, I've not been inside, but from outside they look quite old.
Warrington's nightlife is questionable, there are some good clubs (Panama Jacks, 53 Degrees, Flares, etc) but some you may choose to avoid- they are full of chavs. Stockton Heath (a village about 10 mins form the town centre) has good nightlife, the bars are of a higher class, the people are less violent!
Shopping is quite good, we have a new shopping centre opening in 2007, with 170 (I think) new retail units and a Debenhams.
Don't forget Liverpool and Manchester are also nearby. They both have fab shopping and good nightlife.
I hope I haven't made it sound like a bad place. Of course there are good and bad parts. I've chosen to leave here to go to Uni. To be honest I wouldn't say it's a particulary University type place. There aren't may students. If you want to know anything else, just ask.