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Role of CoA in acetyl-CoA and succinyl-CoA watch
- Thread Starter
- 14-03-2013 21:59
- 14-03-2013 23:31
When a 2C acetyl group is formed from pyruvate in the link reaction, it gets carried by CoA to the matrix in the mitochondria for Krebs Cycle.
CoA is a coenzyme and therefore only assists in functioning of enzymes (without CoA, the Acetyl group wouldn't be able to combine with the 4C oxaloacetate to form 6C Citric), and like enzymes, coenymes don't actually take part in the reaction itself. Consider the role of NADH2, it carries hydrogen to the electron transport chain, but doesn't actually react itself.
At least, that's from my understanding.
Succinyl-CoA is something I haven't come across as it's not on my specification (CCEA), however I'd assume the role of CoA is the similar.