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    My spec says I have to learn The role of the liver in glycogenesis and gluconeogenesis.

    I know that when glucose level falls, glucagon is released which then binds to receptors on the liver which release enzymes to cause Gluconeogenesis (converting glycerol and amino acids into glucose)

    What I dont understand is how the liver has any role in glycogenesis. Since this is only needed when glucose is high, it is under the control of the b cells which release insulin. Insulin can bind to receptors of any body cell and isnt reliant on the liver. this comes back to my question, what is the role of the liver in glycogenesis.

    im doing AQA. Any help will be appreciated

    Insulin stimulates the liver to take up glucose and convert it to glycogen. The liver and skeletal muscle are the major sites of glycogenesis and glycogen storage in the body, glycogenesis only occurs here.

    Hope this helps
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