Hey there! Sign in to join this conversationNew here? Join for free
    • Thread Starter
    Offline

    0
    ReputationRep:
    Inulin clearance is rarely measured clinically because it requires intravenous infusion and bladder catheterisation 'since voluntary bladder emptying may be incomplete', while creatinine is preferred because it is endogenous and released into the bladder at a fairly constant rate, and usually bladder catheterisation is not required. Could anyone tell me why a catheter isn't needed to measure creatinine clearance? :confused: Thank you!
    • Wiki Support Team
    Offline

    12
    ReputationRep:
    Wiki Support Team
    (Original post by laurazzles)
    Inulin clearance is rarely measured clinically because it requires intravenous infusion and bladder catheterisation 'since voluntary bladder emptying may be incomplete', while creatinine is preferred because it is endogenous and released into the bladder at a fairly constant rate, and usually bladder catheterisation is not required. Could anyone tell me why a catheter isn't needed to measure creatinine clearance? :confused: Thank you!
    Inulin would be gold standard in that it would be nigh on exact, which is why you would want to catheterise to get the full amount of urine, however creatine clearance is just an estimation, so it doesn't need to be quite as exact with amount of urine produced (if you don't have to catheterise someone then you won't, it's invasive, unpleasant, and there is always the potential risk of damage/infection)
    Also you normally collect the urine for 24hours for creatine clearance, so you're going to get a fairly accurate amount of urine for that time, the excess in the bladder from incomplete urination is going to be minimal compared to the amount collected
    • Thread Starter
    Offline

    0
    ReputationRep:
    Thank you very much
 
 
 
  • See more of what you like on The Student Room

    You can personalise what you see on TSR. Tell us a little about yourself to get started.

  • Poll
    Brussels sprouts
  • See more of what you like on The Student Room

    You can personalise what you see on TSR. Tell us a little about yourself to get started.

  • The Student Room, Get Revising and Marked by Teachers are trading names of The Student Room Group Ltd.

    Register Number: 04666380 (England and Wales), VAT No. 806 8067 22 Registered Office: International House, Queens Road, Brighton, BN1 3XE

    Quick reply
    Reputation gems: You get these gems as you gain rep from other members for making good contributions and giving helpful advice.