The Student Room Group
Reply 1
The DNA triplet code codes for the manufacture of amino acids and is found in the nucleus
The sequence of amino acids determines the protein which is manufactured
Amino acids are present in the cytoplasm
Proteins are manufactured by ribosomes in the cytoplasm

Therefore:
The DNA code must be transferred from the nucleus to a ribosome: the DNA code is transcribed onto an mRNA molecule
Amino acids must be brought to the ribosome to be assembled into a protein: each tRNA molecule has a codon which allows it to combine with only a particular amino acid; tRNA carries amino acids to the ribosome

Protein synthesis:
The gene that codes for the protein is activated in the DNA
The codons are transcribed onto an mRNA molecule
The mRNA travels from the nucleus to a ribosome through the pores of the nuclear membrane
The mRNA combines with a ribosome
Each tRNA molecule carries a specific amino acid to a ribosome
The tRNA with the correct amino acid to fit the codon on the mRNA enters the ribosome and its amino acid is joined onto the corresponding codon
This continues for the entire mRNA molecule; the amino acids are joined together chemically
Once the entire mRNA molecule has been read, the correct protein (polypeptide) is formed
The protein then folds itself into shape

Hope this helps,

Sen

P.S. It doesn't matter if you don't really understand protein synthesis. Just make sure you learn all the steps - do that and you can still get full marks in a question on it. :smile:

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