6134/01 June 2005 Question on Tuberculosis and Immunity Watch

Chinensis8
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Hi, I'm not so sure where to put this Questio, but here it is.
I have a problem on number 3 part c, d and e.
I checked the markscheme and i still don't get it.
Can someone help?
http://intranet.wellingtoncollege.or....aspx?id=68595
The answers are:
3)

(c) M. bovis antigens similar to tuberculosis / M. fortuitum not similar;
No (secondary response / memory cells to) tuberculosis in A / no immunity / converse; (2)

(d) Immunity to M. fortuitum prevents M. bovis growing and dividing;
M. fortuitum immunises against M. bovis / eq.;
No stimulation of immune response to TB antigens;
M. fortuitum causes antibody production against M. bovis; (2)

(e) BCG won’t protect against TB / more likely to get TB; (1)
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Penguinsaysquack
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(Original post by Chinensis8)
Hi, I'm not so sure where to put this Questio, but here it is.
I have a problem on number 3 part c, d and e.
I checked the markscheme and i still don't get it.
Can someone help?
http://intranet.wellingtoncollege.or....aspx?id=68595
The answers are:
3)

(c) M. bovis antigens similar to tuberculosis / M. fortuitum not similar;
No (secondary response / memory cells to) tuberculosis in A / no immunity / converse; (2)

(d) Immunity to M. fortuitum prevents M. bovis growing and dividing;
M. fortuitum immunises against M. bovis / eq.;
No stimulation of immune response to TB antigens;
M. fortuitum causes antibody production against M. bovis; (2)

(e) BCG won’t protect against TB / more likely to get TB; (1)
This is purely a logic based question more than anything else at this point.

First think of the data they have given you.
For ease of use, TB is tuberculosis, M. B is M. Bovis, and M.F is M. fortuitum

You already know that M. B can be used to vaccinate against TB
In A, the mouse has M.F and then TB but dies. From this you should recognise that it did not provide immunity. The only reason you'd be expected to come up with is that M.F and M.B are not similar (mark scheme stuff)

Does that part make sense now?

d) The clue is in the question. It tells you what M.B needs in order to provide TB immunity. So you should think about why that would NOT happen, the only difference is the M.F before the M.B......

e) This relies on you understanding part d. If you can get that then it is checking you can apply this to a real life example. Have a think about it


BONUS) Seeing as you've had the answers given to you, think about this. If a new rat, rat D is given M.B, THEN M.F and THEN later in life TB, do you think it would live or die?
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