I do:
Biology: I actually really enjoy it. I love human biology anyway, and I've found that I can relate the things I am learning to what is happening in the news (and I can answer some of the questions on University Challenge too!). Biochemistry topics are a bit horrible, but gradually you get used to it.
Chemistry: I can understand almost everything (mainly due to teaching styles). I've found so far it's all manageable and again relates to the world around me... occasionally. Plus the unis love it. It's quite maths-based in places though and I found it difficult to get to grips with some concepts.
English Literature: Love it. Absolutely love it. But the essays are not so great. However, we get to watch films as ways of "viewing different interpretations of the novel/play". I found it a big relief from all my quite linear subjects.
(And Maths, but you said it's a definite no).
If you really like Drama, then do Drama. It is a lot of work (most of my friends do it) but they enjoy it. There are constant write-ups, lines and speeches to learn and plays to read and analyse, but there are some very fun elements too.