Making Medicines Stages Watch

KSmith15
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I have to put the following stages in order but I really don't have a clue!
A. Use of molecular modelling software to predict potentially useful compounds
B. Preparation of a compound in a form in which it can be used as a medicine
C. Comparison with a medicine already used to treat the same condition
D. Extraction of compounds from natural materials such as plants
E. Marketing compound as a new medicine
F. Application to conduct clinical trials
G. Synthesis of new compounds
H. Testing compounds for biological activity
I. trials with low doses given to healthy volunteers
J. Application for product licence
K. Trials with different doses given to different patients
L. Comparison with a placebo
M. Long-term testing using animals
N. Preparation of analogues of molecules that show biological activity.
I would really appreciate some help! :confused:
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username913907
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(Original post by KSmith15)
I have to put the following stages in order but I really don't have a clue!
A. Use of molecular modelling software to predict potentially useful compounds
B. Preparation of a compound in a form in which it can be used as a medicine
C. Comparison with a medicine already used to treat the same condition
D. Extraction of compounds from natural materials such as plants
E. Marketing compound as a new medicine
F. Application to conduct clinical trials
G. Synthesis of new compounds
H. Testing compounds for biological activity
I. trials with low doses given to healthy volunteers
J. Application for product licence
K. Trials with different doses given to different patients
L. Comparison with a placebo
M. Long-term testing using animals
N. Preparation of analogues of molecules that show biological activity.
I would really appreciate some help! :confused:
I can have a good stab at this, but lets hear your best attempt first
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KSmith15
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Ahncdbgfmiklje
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username913907
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(Original post by KSmith15)
Ahncdbgfmiklje
Sounds like a good set to me. The latter part is definitely good, but I might change some of the early bits.

I know that in the past a common way to screen for useful drugs was to extract lots of natural products and screen them on an assay for activity.
Big pharma now use compound databases to screen a large library of molecules for activity against a target, identify good leads and then optimise them with the help of modeling software to help guide development.
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